There are quite a few reasons why a dog may show signs of travel anxiety. One of the main causes is motion sickness. Just like humans, dogs can get carsick. This is especially true for a puppy, whose ears and ability to regulate balance are still developing. Although the pup may grow out of this motion sickness, the association between car travel and feeling sick could remain.
Graphic created by Ancillary K9, a provider of personal protection dog training.